Pilin Kameneero, coordinator of the multiple sclerosis group.
Recently published in the scientific magazine mosque Put the view on the effects resulting from Vitamin D in Permanent sclerosis. According to the results of a clinical trial, High doses of This article was able to amend Disease. Looking at this new scenario, from the Spanish Association of Neuroscience (SenMake sure that these results “are an important progress in knowing the role of this vitamin in the disease and can be considered Positive and clinically relatedAlthough there are certain restrictions, such as the fact that a Significant decrease In the clinical relapse rate. “
In this sense, society confirms that there are doubts about its effect on the clinical progress of the disease, although if new developments are achieved, the possibility of seeing this treatment is like Complementary strategy.
Anna Pilin KamineroCoordinator Multiple sclerosis study group Y SEN relevant neurological immune diseases, keepA cautious position on the use of vitamin D in Multiple stiffness Because there is no solid evidence. However, the results of the MS Trial D-Lay can affect this position. “
Least
He says that this study may have an effect on the clinical practice of neurologists, because “it indicates that giving a high dose in vitamin D can delay the activity of the disease, as shown from a Low the frequency of new injuries And a greater average until the development of the disease. Despite a Statistically significant difference At clinical relapse, activity reduction is a related conclusion in early multiple sclerosis.
Looking at this vision, Kaminero is convinced of that, then The results are repeated in additional studiesSEN “may consider vitamin D supplements in patients with clinical isolated syndrome as a complementary strategy. Patients with severe vitamin D deficiency“.
“Priority average treatments should continue with proven effective.” |
Although the data is promising, the neurologist “still Permanent use of vitamin D has nothing to justify As a standard treatment without additional studies. The rates of the disease should continue in priority with proven effective. “
Despite the evidence for this relationship, vitamin D supplements did not appear, according to the optional effectiveness in Clinical parameters o The results were contradictory.They did not find great benefits In reducing relapses or the development of disability. Instead, smaller experimental studies indicate this High doses of vitamin D They can reduce the activity of the disease that is measured by Magnetic resonance And reduce Return frequency in some patients“.
The limits of research in sclerosis
Regarding the restrictions imposed on the investigation, the specialist remembers that “a A significant decrease in the clinical relapse rateThis raises doubts about its effect on the clinical progress of the disease. The study did not assess whether vitamin D can improve long -term disability. In addition, it was not compared with Other rate treatments for the diseaseSo you cannot conclude if its effect is equivalent or higher. “
So, keep in mind that it is “required More research to determine whether it is vitamin D It should be included in Treatment evidence From multiple sclerosis. In addition, it is necessary to conduct studies that compare vitamin D with modified medications of the disease, as it should focus on improving the disease in your opinion, and its effect on improving biomus, in addition to establishing biological items that allow the therapeutic response.
How vitamin D affects sclerosis
The truth is that spread Multiple stiffness “She has The northern latitude is includedIncrease with the ecotamor in the northern hemisphere. Several reasons were proposed to explain this graduation, such as exposure to radiation UV rays b (UVB) y la Vitamin D. Epidemiological studies have shown that living in areas with greater UVB radiation during childhood is related to Decreased To develop the disease. This danger is also independent of vitamin D levels.
In addition, the neurologist remembers that many studies have also shown this Low levels of vitamin D It is linked to “a Increase the risk of stiffness And the increased risk of relapses after the diagnosis. The mechanisms that explain this association are multi -factor, with a potential effect of genetic and other environmental factors.
The information published in the medical writing contains data, data and data from official institutions and health professionals. However, given any questions related to your health, consult the opposite health specialist.
