Increased physical activity in average age protects from Alzheimer’s disease

Spanish researchers have shown that increasing physical activity and performing continuous and regular exercises during the Mediterranean period, between 45 and … 65 years old, he protects Alzheimer’s disease, at least delaying the appearance of this dementia, which is the most infection of the Spanish population.
The work, which was carried out by scientists from the World Health Institute in Barcelona (ISGLOBAL), a center promoted by the La Caixa Foundation, and the center of the Pasqual Margall Foundation, notes that the increase in physical activity during the entitlement does not reduce the risk factors that only contribute to the emergence of this customer, but rather a filler so that some diseases that do not allow the expression of diagnosis and allowing diagnosis and allowing diagnosis or allowing Diagnosing it. Alzheimer’s.
Current analyzes have documented that physical inactivity is an element that contributes to the emergence of nearly 13 % of Alzheimer’s cases. The reason is that regular exercise reduces the risk of developing this dementia because it reduces the risk factors that facilitate it, such as the performance of the cardiovascular and mental health.
But the Spanish researchers took another step. They have shown that citizens who meet the levels of physical activity recommended by the World Health Organization (WHO) for those in middle age are also developing to the lowest diseases that lead directly to Alzheimer’s disease.
To do this, they continued for a period of four years from 337 people between the ages of 45 and 65 with a family history of this dangerous dementia, whose periodic questionnaires have been implemented measured the level of their physical activity and those who presented nervous imaging tests in order to analyze the effects of exercise on the structure of the brain and their functions.
In order to evaluate the results, they classified the study participants in three groups. “Followers”, which fulfill the recommendations of the World Health Organization, which must be trained between two and a half hours and five hours of proficient physical activity or between an hour and a quarter and a half of intensive exercises. The latter, “unpopular”, practiced, but less than recommended. Another, “stable”, had no activity per week.
The results were conclusive in at least two different aspects. First, those whose physical activity has increased to the recommendations of the World Health Organization, “Followers”, accumulated the amyloid belefa much lower than the rest of the other two groups. Beta amyloid is a protein that hinders the natural nervous communication of the brain and is considered the first disease that is not the evil of Alzheimer’s, the first episode that allows its diagnosis. In addition, they managed to confirm that the greater the increasing increase in physical activity, the lower the presence of this main protein.
The stable has a thinning of the cerebral cortex, which affects the memory and is an early sign of neuropathy
But there was the second verification. The non -corresponding citizens in the control group, who made a type of exercise, had a greater thickness of the cerebral cortex in some areas related to Alzheimer’s disease. This property is the key to the proper performance of memory, so losing weight or detected atrophy in the stable is an early sign of neurological degeneration. Moreover, even the group that practiced a level of activity is lower than recommended by those who had a thickness of greater than the shell than the stable, indicating that any degree of exercises provides benefits.
The investigation also revealed a third difference on the direct benefits of physical exercise. Citizens covered in the study, which provided less diseases associated with Alzheimer’s disease, were to the point that they reached concrete levels of physical activity at a certain time, such as those that achieved a gradual increase in the level of exercise and its long -term support.
“These results enhance the importance of enhancing exercise at an average age as a general health strategy for the prevention of Alzheimer’s disease,” says Eider Arenaza-Urquijo, ISGLOBAL Researcher and the lead author of the study. “The interventions aimed at enhancing the increase in physical activity may be a key to reducing the occurrence of the disease in the future.”